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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T9617 | RdRP-IN-2 | SARS-CoV | |
RdRP-IN-2 is a RNA dependent RNA polymerase (RdRp) inhibitor. It significantly inhibits SARS-CoV-2 RdRp with an IC50 of 41.2 µM.It also inhibits Feline coronavirus (FIPV) replication. | |||
T8886 | NITD-2 | DNA/RNA Synthesis | |
NITD-2 is a dengue virus (DENV) polymerase inhibitor, inhibits the DENV RdRp-mediated RNA elongation. NITD-2 penetrates cell membrane poorly. Dengue virus (DENV) is the most prevalent mosquito- borne viral pathogen in hu... | |||
T9618 | HeE1-2Tyr | SARS-CoV | |
HeE1-2Tyr, a pyridobenzothiazole compound, is a flavivirus RNA dependent RNA polymerases (RdRp) inhibitor. It significantly inhibits West Nile, Dengue and SARS-CoV-2 RdRps (IC50 of 27.6 µM) activity in vitro. | |||
T79234 | RdRP-IN-7 | SARS-CoV | |
RdRP-IN-7, a RNA-dependent RNA polymerase (RdRp) inhibitor, demonstrates efficacy against SARS-CoV-2 infection with an inhibitory concentration (IC50) of 8.2 μM and (IC90) of 14.1 μM, alongside a cytotoxic concentration ... | |||
T81204 | SARS-CoV-2-IN-67 | SARS-CoV | |
SARS-CoV-2-IN-67 (Compound 16), a derivative of vitamin K, exhibits anti-SARS-CoV-2 properties, with an effective concentration (EC50) of 64.8 μM in VeroE6/TMPRSS2 cells, and inhibits SARS-CoV-2 RdRp activity [1]. | |||
T63253 | AVG-233 | DNA/RNA Synthesis , RSV | |
AVG-233 is an orally available RNA-dependent RNA polymerase (RdRp) inhibitor with antiviral activity that blocks respiratory syncytial virus and SARS-CoV-2 replication.AVG-233 is used in the study of respiratory syncytia... | |||
T73253 | EIDD-2749 | 4'-Fluorouridine,4'-FlU ; 4'-Fluorouridine,4'-FlU | |
EIDD-2749 (4'-Fluorouridine), an orally active RdRp inhibitor, effectively inhibits the replication of RSV and SARS-CoV-2. It also demonstrates activity against HCV and lymphocytic choriomeningitis virus (LCMV), highligh... |